Which vaccine is contraindicated in a child with a history of anaphylaxis to neomycin?

The Mumps, Measles, Rubella (MMR) vaccine is contraindicated in a child with a history of anaphylaxis to neomycin due to the presence of neomycin in the vaccine's formulation. Neomycin is an antibiotic that can trigger severe allergic reactions in susceptible individuals. Because a history of anaphylaxis signifies a significant allergy, it is essential to avoid any vaccines containing neomycin to prevent potentially serious allergic reactions.

The Varicella vaccine also contains neomycin, which might suggest that it is also contraindicated; however, the question specifically asks about the MMR vaccine in relation to neomycin. The pneumococcal vaccine and the influenza vaccine do not contain neomycin, making them safe options for children with this particular allergy. This distinction is vital for guiding vaccination practices and ensuring children's safety in the context of their allergies.